Analytes & Panels

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Analytes & Panels

Depression Panels (Human)

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댓글 0건 조회 32회 작성일 25-11-19 10:46

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Human High Sensitivity Cytokine Panel A 
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
GM-CSF 0.415 - 1,700 1:2 1:2 N/A 0.13
IFN-gamma 3.71 - 15,200 1:2 1:2 N/A 0.25
IL-1 beta/IL-1F2 0.34 - 1,400 1:2 1:2 N/A 0.18
IL-2 0.684 - 2,800 1:2 1:2 N/A 0.28
IL-4 7.62 - 7,800* 1:2 1:2 N/R 2.54
IL-5 0.391 - 1,600 1:2 1:2 N/A 0.12
IL-6 0.854 - 3,500 1:2 1:2 N/A 0.31
IL-8/CXCL8 0.879 - 3,600 1:2 1:2 N/R 0.07
IL-10 0.244 - 1,000 1:2 1:2 N/R 0.24
IL-12 p70 6.59 - 27,000 1:2 1:2 N/R 2.96
TNF-alpha 0.757 - 3,100 1:2 1:2 N/A 0.54
VEGF 2.25 - 2,300* 1:2 1:2 N/R 1.35
Human Inflammation Panel
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
Aggrecan 294 - 72000 1:2 1:2 1:2 249
APRIL/TNFSF13 82.3 - 20000 1:2 1:2 1:2 7.95
BAFF/BLyS/TNFSF13B 17.4 - 4200 1:2 1:2 1:2 1.01
CCL5/RANTES 20.6 - 5000 1:2 1:2 1:2 1.8
CD163 5140 - 1250000 1:2 1:2 1:2 530
Chitinase 3-like 1/YKL-40 412 - 100000 1:2 1:2 1:2 3.3
gp130 412 - 100000 1:2 1:2 1:2 11.2
IFN-beta 14.1 - 3450 1:2 1:2 1:2 0.476
IFN-gamma 2.67 - 650 1:2 1:2 1:2 0.22
IL-8/CXCL8 4.12 - 1000 1:2 1:2 1:2 1.8
IL-10 4.1 - 1000 1:2 1:2 1:2 1.6
IL-11 412 - 100000 1:2 1:2 1:2 24.7
IL-12/IL-23 p40 477 - 115000 1:2 1:2 1:2 35.2
IL-19 272 - 66000 1:2 1:2 1:2 64.3
IL-27 309 - 75000 1:2 1:2 1:2 2.7
IL-28A/IFN-lambda 2 144 - 35000 1:2 1:2 1:2 8.6
IL-34 94.7 - 23000 1:2 1:2 1:2 18.7
IL-6R alpha 50 - 64,100 1:2 1:2 1:2 0.6
MMP-1 49.4 - 12000 1:2 1:2 1:2 2.7
MMP-2 276 - 67000 1:2 1:2 1:2 108
MMP-3 82.3 - 20000 1:2 1:2 1:2 5.3
Pentraxin 3/TSG-14 165 - 40000 1:2 1:2 1:2 39.5
BCMA/TNFRSF17 24.7 - 6000 1:50 1:50 1:2 1.2
CD30/TNFRSF8 2.06 - 500 1:2 1:2 1:2 0.1
IL-2 30.9 - 7500 1:2 1:2 1:2 1.8
IL-4 17.3 - 4200 1:2 1:2 1:2 9.3
IL-6 3.25 - 790 1:2 1:2 1:2 1.7
IL-12 p70 144 - 35000 1:2 1:2 1:2 20.2
Osteopontin/OPN 1440 - 350000 1:2 1:2 1:2 413
TNF-alpha 8.23 - 2000 1:2 1:2 1:2 1.2
TNF RI/TNFRSF1A 49.4 - 12000 1:2 1:2 1:2 41
TNF RII/TNFRSF1B 11.1 - 2700 1:2 1:2 1:2 0.5
LIGHT/TNFSF14 8.19 - 1990 1:2 1:2 1:2 0.691
Notes:
- APRIL/TNFSF13 cannot be multiplexed with BCMA/TNFRSF17, CD30/TNFRSF8, TNF RI/TNFRSF1A, or TNF RII/TNFRSF1B
- BAFF/BLyS/TNFSF13B cannot be multiplexed with BCMA/TNFRSF17, or LIGHT/TNFSF14
- IL-12/IL-23 p40 cannot be multiplexed with IL-12 p70
- Use heparin plasma as EDTA and citrate plasma samples are not recommended as anticoagulants due to their chelating properties.
- BCMA/TNFRSF17 cannot be multiplexed with LIGHT/TNFSF14, APRIL/TNFSF13, or BAFF/BLyS/TNFSF13B
- CD30/TNFRSF8 cannot be multiplexed with APRIL/TNFSF13, or LIGHT/TNFSF14
- IL-12 p70 cannot be multiplexed with IL-12/IL-23 p40
- TNF RI/TNFRSF1A cannot be multiplexed with APRIL/TNFSF13, or LIGHT/TNFSF14
- LIGHT/TNFSF14 cannot be multiplexed with TNF RI/TNFRSF1A, BAFF/BLyS/TNFSF13B, BCMA/TNFRSF17, CD30/TNFRSF8, or TNF RII/TNFRSF1B
Human TGF-beta Panel
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
TGF-beta 1 33.3 - 24,300  1:10.7  1:10.7 1:3.57 11.1
TGF-beta 2 17.0 - 12,500  1:10.7  1:10.7 1:3.57 6.8
TGF-beta 3 68.0 - 49,850  1:10.7  1:10.7 1:3.57 14.3
Notes:
- Samples require activation and dilution before assaying. Due to a low level of cross-reactivity of the biotinylated anti-TGF-beta 1 antibody with TGF-beta 2, multiplexing TGF-beta 1 and TGF-beta 2 can result in falsely elevated values for TGF-beta 2 in some sample types.
- Samples require activation and dilution before assaying.
Human Myokine Panel
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
BDNF 20.6 - 5000 1:50 1:2 1:2 0.32
CX3CL1/Fractalkine 617 - 150000 1:2 1:2 1:2 64.8
Follistatin-like 1/FSTL1 1210 - 295000 1:2 1:2 1:2 281
IL-6 3.25 - 790 1:2 1:2 1:2 1.7
IL-15 6.3 - 1550 1:2 1:2 1:2 1.01
LIF 24.7 - 6000 1:2 1:2 1:2 9.31
SPARC 1230 - 300000 1:50 1:50 1:2 97.9
Oncostatin M/OSM 391 - 95000 1:2 1:2 1:2 44.3
Notes:
- IL-6 cannot be multiplexed with Oncostatin M/OSM
- Oncostatin M/OSM cannot be multiplexed with IL-6
Human Neurodegenerative Disorder Panel
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
APP 4120 - 1000000 1:2 1:2 1:2 349
BDNF 20.6 - 5000 1:50 1:2 1:2 0.32
C-Reactive Protein/CRP 119 - 29000 1:200 1:200 1:2 116
Calbindin D 30.9 - 7500 1:2 1:2 1:2 12.3
CCL5/RANTES 20.6 - 5000 1:50 1:50 1:2 1.8
GDNF 6.17 - 1500 1:2 1:2 1:2 0.582
ICAM-1/CD54 3200 - 775,000 1:2 1:2 1:2 87.9
Myeloperoxidase/MPO 123 - 30000 1:50 1:50 1:2 26.2
NCAM-1/CD56 926 - 230000 1:2 1:2 1:2 412
PDGF-AA 4.94 - 1200 1:50 1:2 1:2 0.747
PDGF-BB 12.3 - 3000 1:50 1:50 1:2 0.2
RAGE/AGER 123 - 30000 1:2 1:2 1:2 7.2
S100B 40.4 - 9800 1:2 1:2 1:2 4.34
Serpin E1/PAI-1 18.1 - 4400 1:200 1:200 1:2 0.7
Serpin F1/PEDF 132 - 32000 1:4000 1:4000 1:2 3.66
CCL18/PARC 18.5 - 4500 1:50 1:50 1:2 0.3
VCAM-1/CD106 8850 - 2150000 1:2 1:2 1:2 238
Notes:
- The recommended starting dilution for BDNF in serum is 1:50 and for plasma it is 1:2.
- PDGF-AA cannot be multiplexed with VCAM-1/CD106
- The recommended starting dilution for Serpin F1/PEDF in serum and plasma samples is 1:4,000.
- VCAM-1/CD106 cannot be multiplexed with PDGF-AA
Human Circadian Stress Panel
Analyte Standard Curve(pg/mL) Serum Plasma CellCulture Sensitivity(pg/mL)
Cortisol 686 – 500,000 1:4 1:4 - 686
Melatonin 3.4 – 2,500 1:4 1:4 - 4.3


Notes:
Sample extraction protocols are required for serum/plasma samples. Other sample types (e.g. CSF, culture supernatant, saliva, etc.) do not require sample extraction.


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